Related Patent Info
FORMATION OF THREE-DIMENSIONAL ORGAN FROM PLURIPOTENT STEM CELLS
Inventor | TANIGUCHI, Hideki, etc. |
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Assignee | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY |
Title of Invention | FORMATION OF THREE-DIMENSIONAL ORGAN FROM PLURIPOTENT STEM CELLS |
Abstract | Provided is a method for manufacturing an organ bud using (i) vascular cells, (ii) mesenchymal cells, and (iii) tissue or organ cells, wherein each of (i), (ii), and (iii) has been induced from human pluripotent stem cells. In a preferred embodiment, (iii) is a TBX3 and ADRA1B positive human iPSC-derived hepatocyte and the manufactured organ bud is a liver bud. |