Patent Portfolio

Cell surface marker for high efficiency purification of skeletal muscle lineage cells and skeletal muscle stem cells, and use thereof

Ref. No. AJ251
Appl. No.
（filing date）		 PCT/JP2021/041709（2021/11/12）
Pub. No.
（Pub. date）		 WO2022/102742（2022/5/19）
Priority claim No.
（Priority date）

JP2020-190063(2020/11/16)
Inventor SAKURAI Hidetoshi, et al
Assignee Kyoto University
Title of Invention Cell surface marker for high efficiency purification of skeletal muscle lineage cells and skeletal muscle stem cells, and use thereof
Abstract

The present invention provides a method for producing skeletal muscle stem cells with improved purity, comprising a step for inducing differentiation of pluripotent stem cells into skeletal muscle cells, and a step for recovering, from a cell population in the process of inducing differentiation, cells positive for the cell surface marker FGFR4, CDH13-positive cells, or FGFR4-positive and CDH13-positive cells.
Information
(External link)		 https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2022-102742/AF17D0C1E51B79D585EBFF519E310E8FD901BEC13AC05686E3F1892651DA904B/50/en
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