Patent Portfolio

CrRNA having modified nucleotide

Ref. No. AJ293
Appl. No.
(filing date)
PCT/JP2024/012128(2024/3/26)
Pub. No.
(Pub. date)
WO2024/204287(2024/10/3)
Priority claim No.
(Priority date)

JP 2023-050681(2023/03/27)

Inventor HOTTA Akitsu, et al.
Assignee Kyoto University
Title of Invention CrRNA having modified nucleotide
Abstract

The invention relates to pre-crRNAs having modified nucleotides. More specifically, it relates to pre-crRNAs having specific modifications, allele-specific pre-crRNAs, and methods for producing double-stranded DNA modified cells using these pre-crRNAs.

Comments

The invention makes it possible to improve the efficiency of genome editing using the type I CRISPR-Cas system and to analyze genome editing patterns using this system.

Information
(External link)
https://www.j-platpat.inpit.go.jp/c1801/PU/WO-A-2024-204287/50/en