Patent Portfolio
Method for producing mature cardiomyocytes
| Ref. No. | AJ305 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2025/030152（2025/8/27） |
| Pub. No. （Pub. date） |
WO2026/048885（2026/3/5） |
| Priority claim No. （Priority date） |
JP 2024-148013(2024/08/29) |
| Inventor | YOSHIDA Yoshinori, et al. |
| Assignee | Kyoto University |
| Title of Invention | Method for producing mature cardiomyocytes |
| Abstract | The present disclosure relates to methods for producing mature cardiomyocytes, methods for inducing the maturation of cardiomyocytes, etc. |
| Comments |
According to the present disclosure, promoting the expression of miR-208b-3p and reducing the expression of SIX1 in immature cardiomyocytes makes it possible to induce cardiomyocyte maturation. As a result, the mature cardiomyocytes obtained through this disclosure can be used in transplantation therapy, drug discovery, and disease models. |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1801/PU/WO-A-2026-048885/50/en |
| Tag | Heart (Myocardium) |