Patent Portfolio
Method and kit for promoting proliferation of pancreatic endoderm cells
| Ref. No. | AJ237 |
|---|---|
| Appl. No. （filing date） |
JP2021-005958（2021/1/18） |
| Pub. No. （Pub. date） |
JP2021-112185（2021/8/5） |
| Priority claim No. （Priority date） |
US 62/962,186 (2020/01/17) |
| Patent No. | - |
| Inventor | KAWAGUCHI Yoshiya, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method and kit for promoting proliferation of pancreatic endoderm cells |
| Abstract | Provided is a method of promoting proliferation of PDX1 positive NKX6.1 positive pancreatic endoderm cells, comprising bringing said PDX1 positive NKX6.1 positive cells into contact with a FOXO1 inhibitor and/or a Wnt signal activator. The method enables an efficient production from pluripotent stem cells of pancreatic endocrine cells, such as insulin-secreting cells, which are derived from PDX1 positive NKX6.1 positive pancreatic endoderm cells. |
| Comments |
- |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/JP-2021-005958/F38A7E94042219A790962B50FC27ADB5AF8CCF4F62BA7353D0AD242D53E88CA5/10/en |