Patent Portfolio

Nucleic acid aptamer, RNA molecule, pharmaceutical composition, and template DNA molecule

Ref. No. AJ299
Appl. No.
(filing date)
PCT/JP2025/019682(2025/5/30)
Pub. No.
(Pub. date)
WO2025/249560(2025/12/4)
Priority claim No.
(Priority date)

JP 2024-089308(2024/05/31)

Patent No.

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Inventor SAITO Hirohide, et al.
Assignee Kyoto University
Title of Invention Nucleic acid aptamer, RNA molecule, pharmaceutical composition, and template DNA molecule
Abstract

The present invention relates to nucleic acid aptamers that function as RNA sequences that enable cap-independent translation of mRNA, RNA molecules comprising the nucleic acid aptamers, pharmaceutical compositions containing the RNA molecules, and template DNA molecules.

Comments

The nucleic acid aptamer and mRNA molecule comprising it according to the present invention allow modification by m1Ψ, enabling cap-independent translation. This makes it possible to realize pharmaceutical applications of mRNA.

Information
(External link)
https://www.j-platpat.inpit.go.jp/c1801/PU/WO-A-2025-249560/50/en