Patent Portfolio
Nucleic acid aptamer, RNA molecule, pharmaceutical composition, and template DNA molecule
| Ref. No. | AJ299 |
|---|---|
| Appl. No. (filing date) |
PCT/JP2025/019682(2025/5/30) |
| Pub. No. (Pub. date) |
WO2025/249560(2025/12/4) |
| Priority claim No. (Priority date) |
JP 2024-089308(2024/05/31) |
| Patent No. | - |
| Inventor | SAITO Hirohide, et al. |
| Assignee | Kyoto University |
| Title of Invention | Nucleic acid aptamer, RNA molecule, pharmaceutical composition, and template DNA molecule |
| Abstract | The present invention relates to nucleic acid aptamers that function as RNA sequences that enable cap-independent translation of mRNA, RNA molecules comprising the nucleic acid aptamers, pharmaceutical compositions containing the RNA molecules, and template DNA molecules. |
| Comments |
The nucleic acid aptamer and mRNA molecule comprising it according to the present invention allow modification by m1Ψ, enabling cap-independent translation. This makes it possible to realize pharmaceutical applications of mRNA. |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1801/PU/WO-A-2025-249560/50/en |