Patent Portfolio
Method for producing skeletal muscle progenitor cells
| Ref. No. | AJ155 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2015/086585（2015/12/29） |
| Pub. No. （Pub. date） |
WO2016/108288（2016/7/7） |
| Priority claim No. （Priority date） |
JP2014-267085 (2014/12/29) |
| Patent No. | - |
| Inventor | SAKURAI Hidetoshi, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for producing skeletal muscle progenitor cells |
| Abstract | Provided is a method for inducing differentiation into skeletal muscle progenitor cells from pluripotent stem cells comprising the steps (1) and (2A) or (2B): (1) a step of culturing the pluripotent stem cells in a medium containing a TGF-β inhibitor and a GSK3β inhibitor; (2A) a step of culturing the cells obtained in (1) in a medium containing HGF optionally with IGF1; or (2B) a step of culturing the cells obtained in (1) successively (i) in a medium containing a TGF-β inhibitor, a GSK3β inhibitor, IGF1, HGF and bFGF, (ii) in a medium containing a TGF-β inhibitor, a GSK3β inhibitor and IGF1, and (iii) in a medium containing a TGF-β inhibitor, IGF1 and HGF. |
| Comments |
- |
| Updated date | 2018/5/9 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2016-108288/06F9BC12A14F5A6C810BEB292F7B061FADB9F0AF5D87EAE56857273D27DFD750/50/en |
| Tag | Skeletal muscle |