Patent Portfolio
Method for inducing cerebral cortex neurons
| Ref. No. | AJ169 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2016/062578（2016/4/14） |
| Pub. No. （Pub. date） |
WO2016/167372（2016/10/20） |
| Priority claim No. （Priority date） |
JP2015-082497 (2015/04/14) |
| Patent No. | - |
| Inventor | TAKAHASHI, Jun, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for inducing cerebral cortex neurons |
| Abstract | Provided is a method for producing differentiation of cerebral cortex neurons from pluripotent stem cells, comprising steps of (i) suspension culture of pluripotent stem cells in a medium containing a TGFβ inhibitor, bFGF, a Wnt inhibitor, and a BMP inhibitor, (ii) suspension culture of the cells obtained in (i) in a medium containing a Wnt inhibitor and a BMP inhibitor, and (iii) further culturing the cells obtained in (ii). Subsequent to step (iii), the method may further comprise a step (4) selecting the cell which expresses at least one of the marker proteins selected from the group consisting of CD231, PCDH17 and CDH8. |
| Comments |
- |
| Updated date | 2019/6/13 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2016-167372/BFC744ADF8EA6B8BC7EB428AE50F68CC644BA254A116FC00A2B6D0674DEEAD6B/50/en |
| Tag | Nerve (Neuron) |