Patent Portfolio
Method for inducing exon skipping by genome editing
| Ref. No. | AJ145 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2017/041756（2017/11/21） |
| Pub. No. （Pub. date） |
WO2018/179578（2018/10/4） |
| Priority claim No. （Priority date） |
JP2017-068909 (2017/3/30) |
| Patent No. | - |
| Inventor | LI, Hongmei, etc. |
| Assignee | Kyoto University |
| Title of Invention | Method for inducing exon skipping by genome editing |
| Abstract | Provided is a method for skipping a target exon of a desired gene in a genome using CRISPR-Cas and a guide RNA, characterized in that said guide RNA has such a spacer sequence that the CRISPR-Cas cleavage site is positioned within 80 bases apart either from a splice donor site immediately before the target exon or from a splice acceptor site immediately after the target exon. |
| Comments |
- |
| Updated date | 2018/11/16 |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2018-179578/2887EF46D105D51D87C8A2E453C8FD8ED09C1176BC69BCB5B4C361C511D9625F/50/en |
| Tag | Genome Editing |