Patent Portfolio

Prophylactic drug/therapeutic drug for progressive supranuclear palsy

Ref. No. AJ298
Appl. No.
(filing date)
PCT/JP2024/011319(2024/3/22)
Pub. No.
(Pub. date)
WO2024/195858(2024/9/26)
Priority claim No.
(Priority date)

JP 2023-046944(2023/03/23)

Patent No.

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Inventor INOUE Haruhisa, et al.
Assignee Kyoto University / Taisho Pharmaceutical Co., Ltd.
Title of Invention Prophylactic drug/therapeutic drug for progressive supranuclear palsy
Abstract

The invention relates to a preventive and/or therapeutic agent for progressive supranuclear palsy (hereinafter, sometimes referred to as PSP). More specifically, it relates to a preventive and/or therapeutic agent for neurodegenerative diseases including PSP, which contains as an active ingredient a growth arrest and DNA damage-inducible protein 34 (hereinafter, sometimes referred to as GADD34; also known as protein phosphatase 1 regulatory subunit 15A; hereinafter, sometimes referred to as PPP1R15A, and GADD34 and PPP1R15A may be referred to together) inhibitor, such as guanabenz.

Comments

This invention is expected that small molecule compounds will be used in the treatment of progressive supranuclear palsy.

Information
(External link)
https://www.j-platpat.inpit.go.jp/c1801/PU/WO-A-2024-195858/50/en
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