Patent Portfolio
Method for inducing primed pluripotent stem cells into naive pluripotent stem cells, method for manufacturing naive pluripotent stem cells, kit for naive pluripotent stem cell induction, and naive pluripotent stem cell inducing agent
| Ref. No. | AJ259 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2022/11118（2022/3/11） |
| Pub. No. （Pub. date） |
WO2022/191335（2022/9/15） |
| Priority claim No. （Priority date） |
US 63/159,998（2021/3/12） |
| Inventor | YAMASHITA Jun, et al. |
| Assignee | Kyoto University |
| Title of Invention | Method for inducing primed pluripotent stem cells into naive pluripotent stem cells, method for manufacturing naive pluripotent stem cells, kit for naive pluripotent stem cell induction, and naive pluripotent stem cell inducing agent |
| Abstract | Provided is a method for inducing primed pluripotent stem cells into naive pluripotent stem cells by the addition of an AMP kinase activator into a culture medium and a method for inducing primed pluripotent stem cells into naive pluripotent stem cells, that includes a step in which the primed pluripotent stem cell p38 MAP kinase pathway is activated. Also provided are a naive pluripotent stem cell induction kit for these methods and a naive pluripotent stem cell inducing agent. |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2022-191335/45470BFA703210010660A505266B97CE09A792D927E0DDA8682FBF1D3420F7D5/50/ja |