Related Patent Info
IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF
Inventor | BOBIS-WOZOWICZ, Sylwia, etc. |
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Assignee | UNIWERSYTET JAGIELLONSKI, etc. |
Title of Invention | IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF |
Abstract | Provided is an in vivo delivery system of DNA modifying enzymes comprising stem cell (e.g., iPS cell)-derived extracellular vesicles which are defined by the expression of surface markers and a portion of which contains mRNA of hybrid nucleases, recombinases, integrase, resolvases/invertases or transposases. |