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IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF

Publication No. WO2020/021312
Publication date 2020/01/30
Patent No.

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Inventor BOBIS-WOZOWICZ, Sylwia, etc.
Assignee UNIWERSYTET JAGIELLONSKI, etc.
Title of Invention IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF
Abstract

Provided is an in vivo delivery system of DNA modifying enzymes comprising stem cell (e.g., iPS cell)-derived extracellular vesicles which are defined by the expression of surface markers and a portion of which contains mRNA of hybrid nucleases, recombinases, integrase, resolvases/invertases or transposases.

Updated date 2020/02/28
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