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MITOCHONDRIAL AUGMENTATION THERAPY WITH STEM CELLS ENRICHED WITH FUNCTIONAL MITOCHONDRIA

Inventor YIVGI OHANA, Natalie; IL, etc.
Assignee MINOVIA THERAPEUTICS LTD.
Title of Invention MITOCHONDRIAL AUGMENTATION THERAPY WITH STEM CELLS ENRICHED WITH FUNCTIONAL MITOCHONDRIA
Abstract

Provided is a pharmaceutical composition for use in treating or diminishing debilitating conditions in a subject, comprising at least 105 to 2x107 human stem cells (e.g., iPS cells, mesenchymal stem cells, and so on) per kilogram bodyweight of the subject, wherein the human stem cells are enriched with frozen-thawed healthy functional exogenous mitochondria and wherein the debilitating conditions are selected from the group consisting of aging, age-related diseases and the sequalae of anti-cancer treatments.