Related Patent Info
METHOD FOR GLOMERULAR PODOCYTE INDUCTION, AND METHOD FOR PRODUCING PODOCYTE FROM PLURIPOTENT STEM CELL USING SAID INDUCTION METHOD
| Inventor | NISHINAKAMURA Ryuichi, etc. |
|---|---|
| Assignee | NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY |
| Title of Invention | METHOD FOR GLOMERULAR PODOCYTE INDUCTION, AND METHOD FOR PRODUCING PODOCYTE FROM PLURIPOTENT STEM CELL USING SAID INDUCTION METHOD |
| Abstract | Provided is a method for inducing a glomerular podocytes in vitro comprising steps of (a) culturing a nephron precursor cell, which may be derived from mammalian iPS cells, in a medium containing a Wnt agonist and a ROCK inhibitor, (b) culturing the cell obtained in (a) in a medium containing FGF, and (c) culturing the cell obtained in (b) in a medium including FGF, wherein at least one medium in the step (b) or (c) contains a TGFβ signal pathway inhibitor. |