Related Patent Info
METHOD FOR PRODUCING STEM CELL-DERIVED LACRIMAL GLAND TISSUE
Inventor | NISHIDA, Kohji, etc. |
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Assignee | OSAKA UNIVERSITY |
Title of Invention | METHOD FOR PRODUCING STEM CELL-DERIVED LACRIMAL GLAND TISSUE |
Abstract | Provided is a method for producing stem cell-derived lacrimal gland tissue and is characterized by isolating cells that are positive to both SSEA4 and CD104 from a self-formed ectodermal autonomous multi-zone (SEAM) cell population derived from pluripotent stem cells, and three-dimensionally culturing the obtained cells in a culture medium containing EGF and a ROCK inhibitor, to obtain a cell population that expresses lacrimal gland-associated proteins. |