Related Patent Info

PROMOTER FOR INDUCING DIFFERENTIATION OF INSULIN-PRODUCING CELLS

Inventor KONISHI, Atsushi, etc.
Assignee AJINOMOTO CO., INC.
Title of Invention PROMOTER FOR INDUCING DIFFERENTIATION OF INSULIN-PRODUCING CELLS
Abstract

Provided is a promoter that induces differentiation of pluripotent stem cells into insulin-producing cells, which comprises a compound having an LXR agonist-action. In a preferred embodiment, the said compound is an LXR endogenous ligand such as 22(R)-hydroxycholesterol, 24(S)-hydroxycholesterol, 24(S), 25-epoxycholesterol, or 27-hydroxycholesterol.