Related Patent Info
METHODS OF ENHANCING STEM CELL DIFFERENTIATION INTO BETA CELLS
|PAGLIUCA, Felicia, etc.
|SEMMA THERAPEUTICS, INC.
|Title of Invention
|METHODS OF ENHANCING STEM CELL DIFFERENTIATION INTO BETA CELLS
Disclosed is a method for enhancing stem cell differentiation into a beta cell by using one or more epigenetic modification compound(s) which is selected from a group consisting of a DNA methylation inhibitor, a histone acetyltransferase inhibitor, a histone deacetylase inhibitor (in a preferred embodiment, KD5170, MC1568, or TMP195), a histone methyltransferase inhibitor (in a preferred embodiment, DZNep, GSK126, or EPZ6438), or a bromodomain inhibitor.