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ENHANCED DIFFERENTIATION AND MATURATION OF PLURIPOTENT STEM CELL-DERIVED MYOGENIC CELLS

Inventor PERLINGEIRO, Rita, etc.
Assignee PERLINGEIRO, Rita, etc.
Title of Invention ENHANCED DIFFERENTIATION AND MATURATION OF PLURIPOTENT STEM CELL-DERIVED MYOGENIC CELLS
Abstract

Provided is a method for producing myotube from pluripotent stem cells efficiently, comprising (a) a step of differentiating pluripotent stem cells to myogenic progenitors, and (b) a step of terminally differentiating the myogenic progenitors from (a) into myotubes in the presence of at least one gamma secretase inhibitor.