Related Patent Info

ENHANCED REPROGRAMMING OF SOMATIC CELLS

Inventor ELLING, Ulrich, etc.
Assignee IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH
Title of Invention ENHANCED REPROGRAMMING OF SOMATIC CELLS
Abstract

Provided is a method for efficiently preparing a population of iPS cells, comprising a step of expressing one or more Yamanaka factors selected from Oct3/4, Sox2, Klf4, Myc, Nanog and Lin28, and reducing the amount and/or activity of Menin protein (a putative tumor suppressor coded by Men1 gene) in a population of target cells.