Related Patent Info
INDUCTION OF HEPATOCYTES BY STEM CELL DIFFERENTIATION WITH RNA
|WANG, Jiwu, etc.
|ALLELE BIOTECHNOLOGY & PHARMACEUTICALS, INC.
|Title of Invention
|INDUCTION OF HEPATOCYTES BY STEM CELL DIFFERENTIATION WITH RNA
Provided is a method for inducing differentiation of stem cells into hepatocytes by transfecting a first combination of mRNAs (comprising FoxA2 or Sox 17), a second combination of mRNAs (comprising Tbx3 or Hex), and then a third combination of mRNAs (comprising HNF4a or HNF1a) in the courses of the differentiation.