Related Patent Info
METHOD FOR PRODUCING CELLS POSITIVE FOR PTF1A
|KAWAGUCHI, Yoshiya, etc.
|Title of Invention
|METHOD FOR PRODUCING CELLS POSITIVE FOR PTF1A
The present invention provides a method for producing cells positive for PTF1A, which is considered to be a fate-determining gene for pancreatic development. The method comprises a step of culturing a PDX1-positive cell, which may be derived from an iPS cell, in a medium containing at least one substance selected from the group consisting of (a) at least one selected from the group consisting of adenylate cyclase activators, cAMP phosphodiesterase inhibitors, and cAMP analogs, (b) steroids, and (c) nicotinamide.