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METHOD FOR PRODUCING STEM CELL-DERIVED LACRIMAL GLAND TISSUE

Publication No. WO2019/189640
Publication date 2019/10/03
Patent No.

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Inventor NISHIDA, Kohji, etc.
Assignee OSAKA UNIVERSITY
Title of Invention METHOD FOR PRODUCING STEM CELL-DERIVED LACRIMAL GLAND TISSUE
Abstract

Provided is a method for producing stem cell-derived lacrimal gland tissue and is characterized by isolating cells that are positive to both SSEA4 and CD104 from a self-formed ectodermal autonomous multi-zone (SEAM) cell population derived from pluripotent stem cells, and three-dimensionally culturing the obtained cells in a culture medium containing EGF and a ROCK inhibitor, to obtain a cell population that expresses lacrimal gland-associated proteins.

Updated date 2019/12/04
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