Patent Portfolio
Chimeric antigen receptor-expressing immunocompetent cells
| Ref. No. | AJ240 |
|---|---|
| Appl. No. （filing date） |
PCT/JP2021/022944（2021/6/16） |
| Pub. No. （Pub. date） |
WO/2021/256522（2021/12/23） |
| Priority claim No. （Priority date） |
JP2020-104365(2020/6/17) |
| Inventor | KANEKO, Shin, et al |
| Assignee | KYOTO UNIVERSITY |
| Title of Invention | Chimeric antigen receptor-expressing immunocompetent cells |
| Abstract | The present invention addresses the problems of increasing the cytotoxic activity of immunocompetent cells and increasing the therapeutic effect thereof against diseases such as cancer, and provides immunocompetent cells that have reduced diacylglycerol kinase activity and express the chimeric antigen receptor and a fusion protein containing IL-15 and the IL-15 receptor α subunit. |
| Information (External link) |
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2021-256522/844C014B37DD7FBB69E1544AF63C352416D843F79F35A7BC7EE72AA61C36ED91/50/en |