Patent Portfolio

VIRUS-LIKE PARTICLES AND USE THEREOF

Ref. No. AJ202
Appl. No.
(filing date)
PCT/JP2019/027708(2019/7/12)
Pub. No.
(Pub. date)
WO2020/013317(2020/1/16)
Priority claim No.
(Priority date)

JP2018-133682(2018/07/13)

Patent No.

-

Inventor HOTTA, Akitsu, etc.
Assignee Kyoto University
Title of Invention VIRUS-LIKE PARTICLES AND USE THEREOF
Abstract

Provided is a virus-like particle (VLP) encapsulating a target protein and containing a Gag protein that forms a dimer with the target protein. In a preferred embodiment, either the Gag protein or the target protein is a fusion protein with FK-506 binding protein (FKBP12) and the other is a fusion protein with FKBP12-rapamycin associated protein 1, FRAP1 fragment (FRB), wherein FKBP12 and FRB are bound with rapamycin or a rapamycin derivative in the said dimer.

Information
(External link)
https://www.j-platpat.inpit.go.jp/c1800/PU/WO-A-2020-013317/1397B4CED6E237E7B16E2DAB0C46289F22E0326FC1C2B54BA3FE1B4904F2A2FD/50/en