Patent Portfolio

CARDIOMYOCYTE PROPAGATION PROMOTING AGENT AND USE THEREOF

Ref. No. AJ166
Appl. No. (filing date) PCT/JP2019/004631 (2019/02/08)
Pub. No. (Pub. date) WO2019/156216 (2019/08/15)
Priority claim No. (Priority date)

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Patent No.

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Inventor YOSHIDA, Yoshinori, etc.
Assignee Kyoto University
Title of Invention CARDIOMYOCYTE PROPAGATION PROMOTING AGENT AND USE THEREOF
Abstract

This invention relates to a compound (a retinoic acid receptor agonist, a PI3K inhibitor, or an IDH1 inhibitor) which activates cell cycle and thereby increases propagation efficiency of cardiomyocytes that may be derived from iPS cells, and a propagation method using the compound thereof. In a preferred embodiment, the compound is tamibarotene (AM80: retinoic acid receptor agonist).

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Updated date 2020/02/28
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