CARDIOMYOCYTE PROPAGATION PROMOTING AGENT AND USE THEREOF
Ref. No. | AJ166 |
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Appl. No. (filing date) | PCT/JP2019/004631 (2019/02/08) |
Pub. No. (Pub. date) | WO2019/156216 (2019/08/15) |
Priority claim No. (Priority date) | - |
Patent No. | - |
Inventor | YOSHIDA, Yoshinori, etc. |
Assignee | Kyoto University |
Title of Invention | CARDIOMYOCYTE PROPAGATION PROMOTING AGENT AND USE THEREOF |
Abstract | This invention relates to a compound (a retinoic acid receptor agonist, a PI3K inhibitor, or an IDH1 inhibitor) which activates cell cycle and thereby increases propagation efficiency of cardiomyocytes that may be derived from iPS cells, and a propagation method using the compound thereof. In a preferred embodiment, the compound is tamibarotene (AM80: retinoic acid receptor agonist). |
Comments | - |
Updated date | 2020/02/28 |
Publication |