Related Patent Info

SKELETAL MUSCLE DIFFERENTIATION OF MESODERMAL IPSC DERIVED PROGENITORS

Inventor GIACOMAZZI, Giorgia, etc.
Assignee KATHOLIEKE UNIVERSITEIT LEUVEN
Title of Invention SKELETAL MUSCLE DIFFERENTIATION OF MESODERMAL IPSC DERIVED PROGENITORS
Abstract

Provided is an in vitro method to increase the myogenic potential of an iPSC derived mesodermal progenitor cell by use of a miRNA or a mimic of miR-132, miR-424, and miR-146b, and an inhibitor of miR-34c-5p, an inhibitor of miR-34c-3p, and an inhibitor of miR-362.