Related Patent Info
METHODS AND COMPOSITIONS RELATED TO DIFFERENTIATED LUNG CELLS
| Inventor | KOTTON, Darrell N, etc. |
|---|---|
| Assignee | TRUSTEES OF BOSTON UNIVERSITY |
| Title of Invention | METHODS AND COMPOSITIONS RELATED TO DIFFERENTIATED LUNG CELLS |
| Abstract | Provided is a method for producing induced alveolar epithelial type 2 cells (iAEC2s), comprising a step of contacting a KX2-1+ lung epithelial progenitor cell (e.g., those derived from an iPS cell) with an agonist of Wnt/beta-catenin signaling, a corticosteroid and an agonist of cyclic AMP or the cyclic AMP pathway. |