Related Patent Info
NEURAL CREST CELLS TO REVITALIZE CRANIAL ALLOGRAFTS
Inventor | SHEYN, Dmitriy, etc. |
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Assignee | CEDARS-SINAI MEDICAL CENTER |
Title of Invention | NEURAL CREST CELLS TO REVITALIZE CRANIAL ALLOGRAFTS |
Abstract | Described herein are methods and compositions related to use of cranium-specific iPSC-derived cells that are demonstrated as capable of revitalizing structural allografts. Specifically, coating cranial allografts with mesenchymal stem cells derived from iPSC-derived neural crest cells provides an effective therapeutic avenue for cranial defects. |