Related Patent Info
STEM CELL-DERIVED ASTROCYTES, METHODS OF MAKING AND METHODS OF USE
|STUDER, Lorenz, etc.
|MEMORIAL SLOAN-KETTERING CANCER CENTER
|Title of Invention
|STEM CELL-DERIVED ASTROCYTES, METHODS OF MAKING AND METHODS OF USE
Provided is a method for differentiating pluripotent stem cells in a cell population expressing one or more neural stem cell marker(s) into a cell population comprising at least about 10% differentiated cells expressing one or more glial competent cell marker(s), characterized by a step of promoting nuclear factor I-A (NFIA) signaling in the first cell population.