Related Patent Info
STEM CELL-DERIVED ASTROCYTES, METHODS OF MAKING AND METHODS OF USE
Inventor | STUDER, Lorenz, etc. |
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Assignee | MEMORIAL SLOAN-KETTERING CANCER CENTER |
Title of Invention | STEM CELL-DERIVED ASTROCYTES, METHODS OF MAKING AND METHODS OF USE |
Abstract | Provided is a method for differentiating pluripotent stem cells in a cell population expressing one or more neural stem cell marker(s) into a cell population comprising at least about 10% differentiated cells expressing one or more glial competent cell marker(s), characterized by a step of promoting nuclear factor I-A (NFIA) signaling in the first cell population. |