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NOVEL COMPOUNDS AS DUAL INHIBITORS OF HISTONE METHYLTRANSFERASES AND DNA METHYLTRANSFERASES

Inventor AGUIRRE ENA, Xabier, etc
Assignee FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA
Title of Invention NOVEL COMPOUNDS AS DUAL INHIBITORS OF HISTONE METHYLTRANSFERASES AND DNA METHYLTRANSFERASES
Abstract

Provided are novel 4-aminoquinoline derivatives, which are dual inhibitors of histone methyltransferases and DNA methyltransferases, pharmaceutical compositions containing the same, and their use in medicine, in particular as anticancer agents and as agents for generating induced pluripotent stem cells.