Related Patent Info
USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCY
| Inventor | THEUNISSEN, Thorold, W., etc |
|---|---|
| Assignee | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH, etc |
| Title of Invention | USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCY |
| Abstract | Provided are methods for changing the pluripotency state of a vertebrate cell to a more naive state, the methods comprising: culturing a pluripotent vertebrate cell in the presence of a serine/threonine-protein kinase B-Raf (BRAF) inhibitor, an epidermal growth factor receptor (EGFR) inhibitor, a vascular endothelial growth factor 1 (VEGFR1) inhibitor, or a fibroblast growth factor receptor 1 (FGFR1) inhibitor. |