Related Patent Info
MITOCHONDRIAL INHIBITORS FOR USE IN CULTURING PLURIPOTENT STEM CELLS
| Inventor | TYVOLL, David, Alvin, etc |
|---|---|
| Assignee | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, etc |
| Title of Invention | MITOCHONDRIAL INHIBITORS FOR USE IN CULTURING PLURIPOTENT STEM CELLS |
| Abstract | Provided are heterocyclic compounds that inhibit mitochondrial respiration and lead to the growth and maintained pluripotency of pluripotent stem cells even under ambient oxygen conditions. Exemplified compounds are substituted 5-aminotetrazoles, which are reversible mitochondrial inhibitors. |