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ASSAY FOR CELL SPECIFICATION IN SELF-RENEWING HUMAN PLURIPOTENT STEM CELLS

Inventor MCKAY, Ronald, D.G.
Assignee LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
Title of Invention ASSAY FOR CELL SPECIFICATION IN SELF-RENEWING HUMAN PLURIPOTENT STEM CELLS
Abstract

Provided are in vitro assay systems using pluripotent cells for simulating and modeling early steps in cell specification, differentiation and morphogenesis, enabling drug target identification and drug screening, in which the cells are dissociated to single cells and synchronized to initiate processes of cell specification and morphogenesis.