Related Patent Info
GENERATION OF INDUCED PLURIPOTENT STEM CELLS FROM NORMAL HUMAN MAMMARY EPITHELIAL CELLS
| Inventor | CUI, Xiaojiang etc. |
|---|---|
| Assignee | CEDARS-SINAI MEDICAL CENTER |
| Title of Invention | GENERATION OF INDUCED PLURIPOTENT STEM CELLS FROM NORMAL HUMAN MAMMARY EPITHELIAL CELLS |
| Abstract | Described herein are reprogramming techniques allowing for production of mammary-derived iPSCs ("m-iPSCs"). The m-iPSCs described herein exhibit all the hallmarks of stem cell identity including round cluster, bright colony morphology, clonal expansion, and pluripotent marker expression (alkaline phosphatase expression, Oct-4, nanog, etc.) Further refined techniques allow for generation of m-iPSCs under essentially defined conditions. |