Related Patent Info

OSTEOBLAST AND METHOD FOR PREPARING SAME

Inventor YAMAMOTO, Kenta etc.
Assignee KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION
Title of Invention OSTEOBLAST AND METHOD FOR PREPARING SAME
Abstract

The present invention relates to: a method for preparing an osteoblast from a somatic cell by introducing a bone-related gene or an expression product thereof and a reprogramming-related gene or an expression product thereof to a somatic cell of a mammal, or introducing a reprogramming-related gene or an expression product thereof independently to a somatic cell of a mammal, the method for preparing an osteoblast in which the bone-related gene is at least one gene selected from the group consisting of Runx2 (R), Osterix (O), and Dlx5 (D), and the reprogramming-related gene is at least one gene selected from the group consisting of the Oct family, c-Myc (M), L-Myc (L), the Klf family, Lin-28, and Sox2; and an osteoblast prepared by the abovementioned method.