Related Patent Info
OSTEOBLAST AND METHOD FOR PREPARING SAME
Inventor | YAMAMOTO, Kenta etc. |
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Assignee | KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION |
Title of Invention | OSTEOBLAST AND METHOD FOR PREPARING SAME |
Abstract | The present invention relates to: a method for preparing an osteoblast from a somatic cell by introducing a bone-related gene or an expression product thereof and a reprogramming-related gene or an expression product thereof to a somatic cell of a mammal, or introducing a reprogramming-related gene or an expression product thereof independently to a somatic cell of a mammal, the method for preparing an osteoblast in which the bone-related gene is at least one gene selected from the group consisting of Runx2 (R), Osterix (O), and Dlx5 (D), and the reprogramming-related gene is at least one gene selected from the group consisting of the Oct family, c-Myc (M), L-Myc (L), the Klf family, Lin-28, and Sox2; and an osteoblast prepared by the abovementioned method. |