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REPROGRAMMING CARDIOMYOCYTES WITH ONE TRANSCRIPTION FACTOR

Inventor WANG, Haixia etc.
Assignee THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE
Title of Invention REPROGRAMMING CARDIOMYOCYTES WITH ONE TRANSCRIPTION FACTOR
Abstract

Compositions and methods are described herein for chemically inducing cells that express a single pluripotency transcription factor to change their differentiation state and become cardiac cells, cardiac progenitor cells, cardiomyocytes, or a combination thereof.