Related Patent Info
METHOD FOR REMOVING GENOMICALLY INSTABLE iPS CELLS, AND SYNTHETIC PEPTIDE USED IN SAIS METHOD
Inventor | YOSHIDA Tetsuhiko |
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Assignee | TOAGOSEI CO.,LTD. |
Title of Invention | METHOD FOR REMOVING GENOMICALLY INSTABLE iPS CELLS, AND SYNTHETIC PEPTIDE USED IN SAIS METHOD |
Abstract | Provided are: a method for evaluating the genomic instability of pluripotent stem cells efficiently and with a high degree of reliability; a method for removing, from a culture of pluripotent stem cells to be evaluated, pluripotent stem cells which are identified as being genomically instable by said evaluation method; and a synthetic peptide that can be used in these methods. The methods provided by the present invention include: preparing a culture of target pluripotent stem cells; investigating the level of expression of calreticulin in pluripotent stem cells in said culture; and identifying the genomic stability or genomic instability of said stem cells on the basis of said level of expression of calreticulin. |