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METHOD FOR REMOVING GENOMICALLY INSTABLE iPS CELLS, AND SYNTHETIC PEPTIDE USED IN SAIS METHOD

Inventor YOSHIDA Tetsuhiko
Assignee TOAGOSEI CO.,LTD.
Title of Invention METHOD FOR REMOVING GENOMICALLY INSTABLE iPS CELLS, AND SYNTHETIC PEPTIDE USED IN SAIS METHOD
Abstract

Provided are: a method for evaluating the genomic instability of pluripotent stem cells efficiently and with a high degree of reliability; a method for removing, from a culture of pluripotent stem cells to be evaluated, pluripotent stem cells which are identified as being genomically instable by said evaluation method; and a synthetic peptide that can be used in these methods. The methods provided by the present invention include: preparing a culture of target pluripotent stem cells; investigating the level of expression of calreticulin in pluripotent stem cells in said culture; and identifying the genomic stability or genomic instability of said stem cells on the basis of said level of expression of calreticulin.