Related Patent Info
POLYPEPTIDES, NUCLEIC ACIDS AND USES THEREOF
Inventor | REVERSADE, Bruno |
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Assignee | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
Title of Invention | POLYPEPTIDES, NUCLEIC ACIDS AND USES THEREOF |
Abstract | We describe an ELABELA polypeptide comprising a sequence CXXXRCXXXHSRVPFP (SEQ ID NO: 1), in which X signifies an amino acid residue, such as a sequence selected from the group consisting of: SEQ ID NO: 2 to SEQ ID NO: 18, preferably CLQRRCMPLHSRVPFP (SEQ ID NO: 2), or a fragment, homoiogue, variant or derivative thereof, which polypeptide is capable of maintaining self-renewal and/or pluripotency of a stem cell. |