Related Patent Info

METHODS OF DIFFERENTIATING STEM CELL-DERIVED PROPRIOCEPTORS

Inventor STUDER, Lorenz, etc.
Assignee MEMORIAL SLOAN-KETTERING CANCER CENTER
Title of Invention METHODS OF DIFFERENTIATING STEM CELL-DERIVED PROPRIOCEPTORS
Abstract

Provided is an in vitro method for producing a population of differentiated cells expressing one or more proprioceptor marker from a population of stem cells, which may be a popularion of human iPSCs, comprising steps of contacting the stem cell population with TGFβ/Activin-Nodal inhibitor(s) and then Wnt activator(s) in a certain concentration range.