Related Patent Info
ISOGENIC BLOOD-BRAIN BARRIER MODEL
| Inventor | SHUSTA, Eric, V, etc. |
|---|---|
| Assignee | WISCONSIN ALUMNI RESEARCH FOUNDATION, etc. |
| Title of Invention | ISOGENIC BLOOD-BRAIN BARRIER MODEL |
| Abstract | Provided is a method for inducing blood brain barrier properties in iPSC-derived brain microvascular endothelial cells (BMECs) to generate an isogenic blood brain barrier model, comprising a step of co-culturing iPSC-derived BMECs with a cell type selected from the group consisting of iPSC-derived astrocytes, iPSC-derived neurons, and combinations thereof. |