Related Patent Info
METHODS OF GENERATING T-CELLS FROM STEM CELLS AND IMMUNOTHERAPEUTIC METHODS USING THE T-CELLS
| Inventor | CROOKS, Gay, M, etc. |
|---|---|
| Assignee | THE REGENTS OF THE UNIVERSITY OF CLAIFORNIA |
| Title of Invention | METHODS OF GENERATING T-CELLS FROM STEM CELLS AND IMMUNOTHERAPEUTIC METHODS USING THE T-CELLS |
| Abstract | Provided is a method for preparing a composition of T cells from stem or progenitor cells. The method comprises a step of culturing a three-dimensional cell aggregate comprising: a selected population of stromal cells that express a Notch ligand and a selected population of stem or progenitor cells, wherein the culturing is performed in a serum-free medium comprising insulin, biotin, transferrin, and albumin. |