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PRODUCTION OF VIRUS-RECEPTIVE PLURIPOTENT STEM CELL (PSC)-DERIVED HEPATOCYTES

Inventor KANNEMEIER, Christian, etc.
Assignee CELLULAR DYNAMICS INTERNATIONAL, INC.
Title of Invention PRODUCTION OF VIRUS-RECEPTIVE PLURIPOTENT STEM CELL (PSC)-DERIVED HEPATOCYTES
Abstract

Provided is a method for producing virus-receptive pluripotent stem cell (PSC)-derived hepatocytes comprising steps of (a) obtaining PSC-derived hepatocytes, and (b) culturing the PSC-derived hepatocytes in media comprising cAMP and a Janus kinase inhibitor, thereby producing virus-receptive hepatocytes.