Related Patent Info
MULTI-LINEAGE HEMATOPOIETIC PRECURSOR CELL PRODUCTION BY GENETIC PROGRAMMING
| Inventor | YU, Junying, etc. |
|---|---|
| Assignee | CELLULAR DYNAMICS INTERNATIONAL, INC. |
| Title of Invention | MULTI-LINEAGE HEMATOPOIETIC PRECURSOR CELL PRODUCTION BY GENETIC PROGRAMMING |
| Abstract | Provided is a method for producing hematopoietic precursor cells (HPCs) from pluripotent stem cells (PSCs) comprising steps of (a) providing PSCs comprising at least one expression construct encoding hematopoietic precursor programming genes comprising ETS/ERG, GATA2, and HOXA9, and (b) culturing the PSCs under conditions such that the hematopoietic precursor programming genes are expressed, thereby producing HPCs. |