Related Patent Info

METHODS OF GENERATING NEPHRONS FROM HUMAN PLURIPOTENT STEM CELLS

Inventor BONVENTRE, Joseph, V., etc.
Assignee THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
Title of Invention METHODS OF GENERATING NEPHRONS FROM HUMAN PLURIPOTENT STEM CELLS
Abstract

Provided is a method for differentiating human pluripotent stem cells into multipotent nephron progenitor cells (NPCs) that can form nephron-like structures. The method enables generation of SIX2+SALL1+WT1+PAX2+ NPCs.