Related Patent Info
MATURATION OF MAMMALIAN HEPATOCYTES
Inventor | KÜPPERS-MUNTHER, Barbara |
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Assignee | TAKARA BIO EUROPE AB |
Title of Invention | MATURATION OF MAMMALIAN HEPATOCYTES |
Abstract | Provided is a method for promoting maturation of mammalian hepatocytes including human iPS cell-derived hepatocytes, comprising a step of exposing said hepatocytes to at least one maturation factor selected from the group consisting of Src kinase inhibitors, vitamin D derivatives, hypoxia inducing compounds, sphingosine derivatives, PPARs activators, PAF, PKC inhibitors, and combinations thereof. |