Related Patent Info
ENGINEERED ADULT-LIKE HUMAN HEART TISSUE
Inventor | VUNJAK-NOVAKOVIC, Gordana, etc. |
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Assignee | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
Title of Invention | ENGINEERED ADULT-LIKE HUMAN HEART TISSUE |
Abstract | Provided is a method for engineering three-dimensional functional adult cardiac tissue from iPS cell-derived cardiomyocytes comprising a step of electromechanically conditioning the derived cardiomyocytes, wherein the electromechanical conditioning includes a step of exposing the derived cardiomyocytes to electromechanical stimuli that increases in intensity over a period of time. |