Related Patent Info
REVERSION OF PRIMED PLURIPOTENT STEM CELLS TO NAIVE PLURIPOTENT STEM CELLS
| Inventor | KIME, Cody, etc. |
|---|---|
| Assignee | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE |
| Title of Invention | REVERSION OF PRIMED PLURIPOTENT STEM CELLS TO NAIVE PLURIPOTENT STEM CELLS |
| Abstract | Provided is a method for deriving a naive pluripotent stem cell comprising a step of culturing a primed pluripotent stem cell in a culture medium containing an effective amount of a lysophosphatidic acid receptor (LPAR) agonist, thereby reverting the primed pluripotent stem cell to a naive pluripotent stem cell. |