Related Patent Info

METHOD FOR PRODUCTION OF INSULIN-PRODUCING CELLS

Inventor MAMIDI, Anant, etc.
Assignee UNIVERSITY OF COPENHAGEN
Title of Invention METHOD FOR PRODUCTION OF INSULIN-PRODUCING CELLS
Abstract

Provided is a method for differentiating cells into insulin-producing βcells, comprising steps of i) providing a pancreatic progenitor cell population comprising at least one cell capable of differentiation and ii) incubating said cell population in the presence of a Yap1 inhibitor; thereby obtaining a cell population enriched for insulin-producing βcells; wherein the said cell capable of differentiation is a human iPS cell.