Related Patent Info

REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREFORE

Inventor EVANS, Ronald, etc.
Assignee SALK INSTITUTE FOR BIOLOGICAL STUDIES
Title of Invention REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREFORE
Abstract

Provided is a method for selecting a mammalian induced pluripotent stem cell progenitor comprising a step of isolating an induced pluripotent stem cell progenitor expressing one or more of Oct4, Sox2, Klf4 and cMyc, and having increased expression of an estrogen related receptor relative to a reference cell, thereby selecting an induced pluripotent stem cell progenitor which generates an iPSC at high efficiency.