Related Patent Info
REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREFORE
Inventor | EVANS, Ronald, etc. |
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Assignee | SALK INSTITUTE FOR BIOLOGICAL STUDIES |
Title of Invention | REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREFORE |
Abstract | Provided is a method for selecting a mammalian induced pluripotent stem cell progenitor comprising a step of isolating an induced pluripotent stem cell progenitor expressing one or more of Oct4, Sox2, Klf4 and cMyc, and having increased expression of an estrogen related receptor relative to a reference cell, thereby selecting an induced pluripotent stem cell progenitor which generates an iPSC at high efficiency. |