Related Patent Info

METHOD ANK KIT FOR REPROGRAMMING SOMATIC CELLS

Inventor BULAVIN, Dmitry, etc.
Assignee INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), etc.
Title of Invention METHOD ANK KIT FOR REPROGRAMMING SOMATIC CELLS
Abstract

The present invention relates to a method for reprogramming a human somatic cell into a human iPS cell by using a specific combination of small-molecule compounds comprising a step of culturing said somatic cell in the presence of at least a combination of a DNA methyltransferase (DNMT) inhibitor, a Sirtuin inhibitor and a poly (ADP-ribose) polymerase (PARP) inhibitor.